Homework Solution: The following figures show the Lineweaver-Burk plots of two different inhibitor…

    The following figures show the Lineweaver-Burk plots of two different inhibitor experiments. Identify the mechanism of inhibition for each. Experiment 1 Experiment 2: with inhibitor with inhibitor without inhibitor without inhibitor 始) Type of inhibition for Experiment 1 O competitive inhibition Type of inhibition for Experiment 2: O uncompetitive inhibition
    The following figures show the Lineweaver-Burk plots of two different inhibitor experiments. Identify the mechanism of inhibition for each. Type of inhibition for Experiment 1: competitive inhibition noncompetitive inhibition uncompetitive inhibiton Type of inhibition for Experiment 2: uncompetitive inhibition competitive inhibition noncompetitive inhibiton Inhibition mechanism for Experiment 1: Inhibitor binds to both free E and ES complex with identical binding constants. Inhibitor binds to both free E and o ES complex with different binding constants. Inhibitor binds only to free E. Inhibitor binds only to ES complex. Inhibition mechanism for Experiment 2: Inhibitor binds only to free E. Inhibitor binds to both free E and ES complex with identical binding constants. Inhibitor binds only to ES complex. Inhibitor binds to both free E and ES complex with different binding constants.

    Expert Answer

    The subjoined figures demonstration the Lineweaver-Burk plots of brace contrariant inhibitor exemplifications. Identify the agency of discountenance ce each. Exemplification 1 Exemplification 2: with inhibitor with inhibitor outside inhibitor outside inhibitor 始) Likeness of discountenance ce Exemplification 1 O competitive discountenance Likeness of discountenance ce Exemplification 2: O uncompetitive discountenance

    The subjoined figures demonstration the Lineweaver-Burk plots of brace contrariant inhibitor exemplifications. Identify the agency of discountenance ce each. Likeness of discountenance ce Exemplification 1: competitive discountenance noncompetitive discountenance uncompetitive inhibiton Likeness of discountenance ce Exemplification 2: uncompetitive discountenance competitive discountenance noncompetitive inhibiton Discountenance agency ce Exemplification 1: Inhibitor binds to twain unconditional E and ES deep with selfsame stringent constants. Inhibitor binds to twain unconditional E and o ES deep with contrariant stringent constants. Inhibitor binds simply to unconditional E. Inhibitor binds simply to ES deep. Discountenance agency ce Exemplification 2: Inhibitor binds simply to unconditional E. Inhibitor binds to twain unconditional E and ES deep with selfsame stringent constants. Inhibitor binds simply to ES deep. Inhibitor binds to twain unconditional E and ES deep with contrariant stringent constants.

    Expert Retort

    I) In exemplification individual the likeness of discountenance is competetive discountenance.

    The agency compromised is inhibitor binds simply to Enzyme

    II) Likeness of discountenance in exemplification uncompetetive discountenance

    The agency compromised is Inhibitor binds to enzyme substrate deep(ES deep